A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues

Autor: Dominik Saul, Robyn Laura Kosinsky, Elizabeth J. Atkinson, Madison L. Doolittle, Xu Zhang, Nathan K. LeBrasseur, Robert J. Pignolo, Paul D. Robbins, Laura J. Niedernhofer, Yuji Ikeno, Diana Jurk, João F. Passos, LaTonya J. Hickson, Ailing Xue, David G. Monroe, Tamara Tchkonia, James L. Kirkland, Joshua N. Farr, Sundeep Khosla
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-32552-1
Popis: Identification of senescent cells in vivo remains a challenging task. Here the authors present and validate a senescence gene set called SenMayo enriched in human and murine aged tissues.
Databáze: Directory of Open Access Journals