Screening for Mutations in Hereditary Cancer Susceptibility Genes in a Region with High Endogamy in Brazil

Autor: Polyanna Oliveira, Paula Correa, Angelina Acosta, Juliana Freitas, Taísa Machado-Lopes, Thais Bomfim-Palma, Ândrea Ribeiro-dos-Santos, Sidney Santos, Roberto Nascimento, Ivana Nascimento, Kiyoko Abe-Sandes
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Global Medical Genetics, Vol 10, Iss 04, Pp 376-381 (2023)
Druh dokumentu: article
ISSN: 2699-9404
DOI: 10.1055/s-0043-1777449
Popis: Introduction Cancer is a multifactorial disease dependent on the influence of genetic and environmental factors. About 10% of cancers are associated with germline mutations, which predispose to a higher risk of developing cancer. Currently, the use of panels that identify susceptibility and/or association genes cancer has been increasingly used, both in clinical practice and in scientific research.
Databáze: Directory of Open Access Journals