Extrahepatic portal vein obstruction with parkinsonism and symmetric hyperintense basal ganglia on T1 weighted MRI

Autor: Jayalakshmi Sita, Borgohain Rupam, Mohandas S
Jazyk: angličtina
Rok vydání: 2006
Předmět:
Zdroj: Annals of Indian Academy of Neurology, Vol 9, Iss 1, Pp 46-48 (2006)
Druh dokumentu: article
ISSN: 0972-2327
Popis: Abnormal high signal in the globus pallidus on T1 weighted magnetic resonance imaging (MRI) of the brain has been well described in patients with chronic liver disease. It may be related to liver dysfunction or portal-systemic shunting. We report a case of extra hepatic portal vein obstruction with portal hypertension and esophageal varices that presented with extra pyramidal features. T1 weighted MRI brain scans showed increased symmetrical signal intensities in the basal ganglia. Normal hepatic function in this patient emphasizes the role of portal- systemic communications in the development of these hyperintensities, which may be due to deposition of paramagnetic substances like manganese in the basal ganglia.
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