Expression of molecular lymphatic markers in human choroid
| Autor: | S. R. Nogovitsina |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Acta Biomedica Scientifica, Vol 1, Iss 5, Pp 114-116 (2016) |
| Druh dokumentu: | article |
| ISSN: | 2541-9420 2587-9596 |
| DOI: | 10.12737/23404 |
| Popis: | The purpose of this study was to research lymphatic outflow tract in the human choroid. Using a light microscopy and immunohistochemistry, structure of the choroid was investigated. We used antibodies against lymphatic endothelial-specific markers Prox-1, LYVE-1, Podoplanin, endothelial blood vessels marker CD34 and fibroblasts growth factor receptor FGFR. The choroid was found to contain lymphatic canals in choroidal stroma and a layer of choriocapillaris, and lymphatic lacunae in the suprachoroid lamina, limited endothelium-like cells, positively stained for markers of lymphatic vessels Prox-1, LYVE-1, Podoplanin, and fibroblasts and pigment cells. These endothelium-like cells were shown positive Prox-1, LYVE-1 and Podoplanin staining and negative CD34 staining; therefore we consider that these canals and lacunae are lymphatic structures. |
| Databáze: | Directory of Open Access Journals |
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