Impaired vascular function among young users of anabolic–androgenic steroids

Autor:	Helene Melsom Tungesvik, Astrid Bjørnebekk, Jonny Hisdal
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Anabolic–androgenic steroids Flow-mediated dilation Carotid artery reactivity Vascular health Medicine Science
Zdroj:	Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Druh dokumentu:	article
ISSN:	2045-2322
DOI:	10.1038/s41598-024-70110-5
Popis:	Abstract Supraphysiological doses of anabolic–androgenic steroids (AAS) is popular among recreational weightlifters and bodybuilders due to the performance-enhancing properties but is also associated with adverse cardiovascular effects. The knowledge about how AAS affect the vasculature is limited, although results from previous studies suggest alterations in vasoreactivity and morphology. In the present study we investigate the association between long-term use of AAS and vascular function. Hundred and twenty-three males were included in the study, 56 of them current AAS users and 67 weightlifting controls. Vascular function was evaluated by carotid artery reactivity and flow-mediated dilation. AAS users had significantly reduced carotid artery reactivity (p
Databáze:	Directory of Open Access Journals
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