Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes

Autor: Meghan S. Vermillion, Jun Lei, Yahya Shabi, Victoria K. Baxter, Nathan P. Crilly, Michael McLane, Diane E. Griffin, Andrew Pekosz, Sabra L. Klein, Irina Burd
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms14575
Popis: Zika virus infection of pregnant women is associated with congenital neurological disorders. Here, Vermillionet al. develop an immunocompetent mouse model for identification of factors at the maternal-fetal interface that contribute to adverse perinatal outcomes.
Databáze: Directory of Open Access Journals