Exploring the Feasibility of Cell-Free Synthesis as a Platform for Polyhydroxyalkanoate (PHA) Production: Opportunities and Challenges

Autor:	Huaming Dong, Xue Yang, Jingjing Shi, Chunqiao Xiao, Yanfei Zhang
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	cell-free synthesis system Polyhydroxyalkanoate (PHA) PHA synthesis pathway multienzyme cascade system Organic chemistry QD241-441
Zdroj:	Polymers, Vol 15, Iss 10, p 2333 (2023)
Druh dokumentu:	article
ISSN:	2073-4360
DOI:	10.3390/polym15102333
Popis:	The extensive utilization of traditional petroleum-based plastics has resulted in significant damage to the natural environment and ecological systems, highlighting the urgent need for sustainable alternatives. Polyhydroxyalkanoates (PHAs) have emerged as promising bioplastics that can compete with petroleum-based plastics. However, their production technology currently faces several challenges, primarily focused on high costs. Cell-free biotechnologies have shown significant potential for PHA production; however, despite recent progress, several challenges still need to be overcome. In this review, we focus on the status of cell-free PHA synthesis and compare it with microbial cell-based PHA synthesis in terms of advantages and drawbacks. Finally, we present prospects for the development of cell-free PHA synthesis.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/079caf8a486241b09b9f93bcb14b4acd Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.