Diagnostic value of combined pleural interleukin-33, adenosine deaminase and peripheral blood tuberculosis T cell spot detection TB for tuberculous pleurisy

Autor:	Jin Fenhua, Wang Daohui, Lin Hui, Xia Xiaodong, Huang Wen
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Tuberculosis Pleural effusion Interleukin-33 Adenosine deaminase Tuberculosis T cell spot detection Infectious and parasitic diseases RC109-216
Zdroj:	BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-8 (2021)
Druh dokumentu:	article
ISSN:	1471-2334
DOI:	10.1186/s12879-021-06575-w
Popis:	Abstract Background To investigate the correlation between pleural fluid interleukin-33 (IL-33) and adenosine deaminase (ADA) and peripheral blood tuberculosis T cell spot detection (T-SPOT.TB), and the combined value of the three tests for the diagnosis of tuberculous pleurisy. Methods 79 patients with pleural effusion admitted from June 2017 to December 2018 were enrolled. They were divided into tuberculous pleural effusion (TPE) group (57 cases, 72.2%) and malignant pleural effusion group (17 cases, 21.5%), pneumonia-like pleural effusion group (5 cases, 6.3%). Correlation between pleural fluid IL-33, pleural effusion ADA and peripheral blood T-SPOT.TB was analyzed, comparison of the three separate and combined diagnostic efficacy was also performed. Results The levels of IL-33, ADA and peripheral blood T-SPOT.TB in patients with TPE were significantly higher than those in non-TPE (P
Databáze:	Directory of Open Access Journals
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