Assessing the sensitivity of placental growth factor and soluble fms-like tyrosine kinase 1 at 36 weeks’ gestation to predict small-for-gestational-age infants or late-onset preeclampsia: a prospective nested case-control study

Autor:	Teresa M. MacDonald, Chuong Tran, Tu’uhevaha J. Kaitu’u-Lino, Shaun P. Brennecke, Richard J. Hiscock, Lisa Hui, Kirsten M. Dane, Anna L. Middleton, Ping Cannon, Susan P. Walker, Stephen Tong
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	Biomarker Fetal growth restriction Late-onset Placental growth factor Preeclampsia Small-for-gestational-age Gynecology and obstetrics RG1-991
Zdroj:	BMC Pregnancy and Childbirth, Vol 18, Iss 1, Pp 1-12 (2018)
Druh dokumentu:	article
ISSN:	1471-2393
DOI:	10.1186/s12884-018-1992-x
Popis:	Abstract Background Fetal growth restriction is a disorder of placental dysfunction with three to four-fold increased risk of stillbirth. Fetal growth restriction has pathophysiological features in common with preeclampsia. We hypothesised that angiogenesis-related factors in maternal plasma, known to predict preeclampsia, may also detect fetal growth restriction at 36 weeks’ gestation. We therefore set out to determine the diagnostic performance of soluble fms-like tyrosine kinase 1 (sFlt-1), placental growth factor (PlGF), and the sFlt-1:PlGF ratio, measured at 36 weeks’ gestation, in identifying women who subsequently give birth to small-for-gestational-age (SGA; birthweight
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/e078a64c4e14495884693b89355f6c86 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.