Intravascular laser irradiation of blood as novel migraine treatment: an observational study

Autor: Hsin-Hung Chen, Chun-Yu Lin, Shean-Jen Chen, Wan-Yun Huang, Chien-Wei Kuo, Shin-Tsu Chang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: European Journal of Medical Research, Vol 28, Iss 1, Pp 1-8 (2023)
Druh dokumentu: article
ISSN: 2047-783X
14310813
DOI: 10.1186/s40001-023-01438-3
Popis: Abstract Background Migraine is one of four major chronic diseases that cause disability. Decreases in regional cerebral blood flow (rCBF) occur during migraine attacks. Laser therapy is extensively employed in treating other vascular diseases; nevertheless, its effectiveness in migraine management remains largely unknown. Therefore, we evaluated the effect of low-level intravascular laser irradiation of blood (ILIB) therapy in patients with migraine. Methods We performed an observational case–control study in 24 patients suffering from migraine. Patients were divided into an ILIB treatment group and a traditional rehabilitation group. This study performed clinical assessments and single-photon emission computed tomography (SPECT) prior to and after the treatment and 1 month later. Changes in rCBF-SPECT between groups and between timepoints were compared to clinical outcomes. Results Nine patients undergoing rehabilitation and fifteen patients undergoing ILIB were studied from baseline to 1 month follow-up. The ILIB group, visual analog scale for pain (P = 0.001), Montreal Cognitive Assessment (P = 0.003), and Athens Insomnia Scale (P
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