Possitive correlation between adipocyte fatty acid-binding protein and epicardial fat in patients with a family history of cardiovascular disesase
Autor: | Eliska Sovova, Milan Sova, Jana Zapletalova, David Stejskal, Marketa Sovova, Marketa Kaletova, Gabriela Svobodova, Irena Kuca, Michal Janak, Milan Kaminek |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Biomedical Papers, Vol 161, Iss 2, Pp 174-178 (2017) |
Druh dokumentu: | article |
ISSN: | 1213-8118 1804-7521 |
DOI: | 10.5507/bp.2017.018 |
Popis: | Background: Adipocyte fatty acid-binding protein (A-FABP) is a promising link between metabolic syndrome and atherosclerosis. Epicardial fat (EPI) is an independent risk factor for cardiovascular disease (CVD). Objective: The aim of this pilot study was to evaluate the correlation between EPI and A-FABP in asymptomatic patients with a family history of CVD. Methods: 59 subjects (39 males) (median = 54 years old) were enrolled in the study and their EPI thickness and A-FABP levels were assessed. Results: EPI was found in 46 patients (77.9%). There were positive correlations between EPI and A-FABP (r=0.336; P=0.010), age (r=0.526; P |
Databáze: | Directory of Open Access Journals |
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