Emerging Multifunctional Carbon‐Nanomaterial‐Based Biosensors for Cancer Diagnosis

Autor: Jolitta S. J. Britto, Xinwei Guan, Thi Kim Anh Tran, Zhihao Lei, Rohan Bahadur, Vaishwik Patel, Xiangwei Zhang, Sharon L. Wong, Ajayan Vinu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Small Science, Vol 4, Iss 3, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2688-4046
DOI: 10.1002/smsc.202300221
Popis: Despite significant advancements in medical technology, cancer remains the world's second‐leading cause of death, largely attributed to late‐stage diagnoses. While traditional cancer detection methodologies offer foundational insights, they often lack the specificity, affordability, and sensitivity for early‐stage identification. In this context, the development of biosensors offers a distinct possibility for the precise and rapid identification of cancer biomarkers. Carbon nanomaterials, including graphene, carbon nitride, carbon quantum dots, and other carbon‐based nanostructures, are highly promising for cancer detection. Their simplicity, high sensitivity, and cost‐effectiveness contribute to their potential in this field. This review aims to elucidate the potential of emerging carbon‐nanomaterial‐based biosensors for early cancer diagnosis. The relevance of the various biosensor mechanisms and their performance to the physicochemical properties of carbon nanomaterials is discussed in depth, focusing on demonstrating broad methodologies for creating performance biosensors. Diverse carbon‐nanomaterial‐based detection techniques, such as electrochemical, fluorescence, surface plasmon resonance, electrochemiluminescence, and quartz crystal microbalance, are emphasized for early cancer detection. At last, a summary of existing challenges and future outlook in this promising field is elaborated.
Databáze: Directory of Open Access Journals