| Autor: |
Disha Mishra, Puja Khare, Dhananjay K. Singh, Vineet Yadav, Suaib Luqman, P.V. Ajaya Kumar, Karuna Shanker |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Carbohydrate Polymer Technologies and Applications, Vol 2, Iss , Pp 100152- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2666-8939 |
| DOI: |
10.1016/j.carpta.2021.100152 |
| Popis: |
In this work, the Ocimum basilicum L. extract (OCE) was encapsulated in a cellulose nanofiber/chitosan composite system (CNF/CH) and examined for phenolic release, antioxidant, and antibacterial activities. The prepared OCE loaded composite had a smooth and porous surface with a high swelling index (60 mL g−1). The zeta potential of the CNF/CH was 18.7±0.8 mV. The fabricated CNF/CH exhibited excellent total antioxidant activity (598 µgAAeq mg−1), total phenolic content (62.4 µgGAeq mg−1) and DPPH (1, 1-diphenyl-2 picrylhydrazyl) (83%) scavenging activity. In vitro release experiment demonstrated the prolonged-release (up to 50% after 6 hours) of phenolic from CNF/CH due to a concentration gradient between CNF/CH and the solution. The release of phenolic occurs through both fickian and non-fickian diffusion. The CNF/CH exhibited excellent antibacterial activity against Gram-positive (Streptococcus mutans) and Gram-negative (Salmonella typhimurium) bacterial strains with the inhibition percentage 97% and 99%, respectively. Results suggest that CNF/CH is a promising biomaterial for the development of the phenolic rich material and maintain the antioxidant activities of OCE. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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