Clinical and immunological features and treatment of myasthenia gravis in the elderly (review)

Autor: T. M. Alekseeva, V. D. Kosachev, A. N. Khalmurzina
Jazyk: ruština
Rok vydání: 2019
Předmět:
Zdroj: Нервно-мышечные болезни, Vol 6, Iss 3, Pp 10-16 (2019)
Druh dokumentu: article
ISSN: 2222-8721
2413-0443
DOI: 10.17650/2222-8721-2016-6-3-10-16
Popis: A literature review on the peculiarities of the diagnosis, course and treatment of myasthenia gravis in the elderly has been done. Despite the fact that myasthenia gravis is a disease of the young and middle-aged, in recent years, several authors observe an increased incidence among the elderly. A proper diagnosis in this age group tend to cause difficulties, and concomitant diseases complicate the choice of therapeutic approach which includes: acetylcholinesterase inhibitors, steroids, immunosuppressants, intravenous immunoglobulins and plasmapheresis. Thymectomy in older age groups, except for the presence of thymoma, due to side effects and the lack of a strong evidence base, is not widely held. The question of the effectiveness and optimal therapeutic approach of myasthenia gravis in elderly patients is still not fully resolved.
Databáze: Directory of Open Access Journals