Maternal anaemia during early pregnancy and the risk of neonatal outcomes: a prospective cohort study in Central China

Autor: Xiaoying Liu, Mengting Sun, Jianhui Wei, Senmao Zhang, Jing Shu, Taowei Zhong, Yiping Liu, Jiabi Qin, Yige Chen, Xinli Song
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMJ Paediatrics Open, Vol 8, Iss 1 (2024)
Druh dokumentu: article
ISSN: 2399-9772
DOI: 10.1136/bmjpo-2023-001931
Popis: Background The purpose of this study was to explore the association between anaemia during early pregnancy and the risk of neonatal outcomes.Methods We collected clinical data from pregnant women (≥18 years) who received their first antenatal care between 8 and 14 weeks of gestation in Hunan Provincial Maternal and Child Health Care Hospital. Multiple logistic regression models and restricted cubic spline regression models were used to analyse the association between anaemia during early pregnancy and the risk of neonatal outcomes. In addition, sensitivity analysis was further performed to assess the robustness of the results.Results The prospective cohort study ultimately included 34 087 singleton pregnancies. In this study, the rate of anaemia during early pregnancy was 16.3%. Our data showed that there was a positive relationship between the rate of preterm birth, low birth weight as well as small for gestational age (SGA) and the severity of maternal anaemia (Ptrend
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