| Autor: |
Mariana Fernandes, Matteo Spanetta, Giorgio Vetrugno, Marzia Nuccetelli, Fabio Placidi, Alessandro Castelli, Natalia Manfredi, Francesca Izzi, Giuseppina Laganà, Sergio Bernardini, Nicola Biagio Mercuri, Claudio Liguori |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Brain, Behavior, & Immunity - Health, Vol 42, Iss , Pp 100875- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2666-3546 |
| DOI: |
10.1016/j.bbih.2024.100875 |
| Popis: |
Background: Interleukin-6 (IL-6) represents one of the main molecules involved in inflammatory responses, which can be altered in either patients with cognitive impairment or obstructive sleep apnea (OSA). The present study aimed to evaluate serum IL-6 levels and cognitive performance in patients with severe OSA (Apnea-Hypopnea Index - AHI >30/h). Methods: Thirty patients with severe OSA were compared to 15 controls similar in age, sex, and Body Mass Index. All patients underwent a sleep medicine interview, including the Epworth Sleepiness Scale (ESS), a polygraphic cardiorespiratory recording, the Montreal Cognitive Assessment (MoCA), and a blood sample for serum IL-6 assessment. Results: OSA patients presented higher IL-6 serum levels (Md = 7.38) than controls (Md = 2.20, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
