Elevated circulating monocytes and monocyte activation in COVID-19 convalescent individuals

Autor: Juwon Park, Logan S. Dean, Boonyanudh Jiyarom, Louie Mar Gangcuangco, Parthav Shah, Thomas Awamura, Lauren L. Ching, Vivek R. Nerurkar, Dominic C. Chow, Fritzie Igno, Cecilia M. Shikuma, Gehan Devendra
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Immunology, Vol 14 (2023)
Druh dokumentu: article
ISSN: 1664-3224
DOI: 10.3389/fimmu.2023.1151780
Popis: BackgroundMonocytes and macrophages play a pivotal role in inflammation during acute SARS-CoV-2 infection. However, their contribution to the development of post-acute sequelae of SARS-CoV-2 infection (PASC) are not fully elucidated.MethodsA cross-sectional study was conducted comparing plasma cytokine and monocyte levels among three groups: participants with pulmonary PASC (PPASC) with a reduced predicted diffusing capacity for carbon monoxide [DLCOc,
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