Adhesin RadD: the secret weapon of Fusobacterium nucleatum

Autor:	Dingjiacheng Jia, Shujie Chen
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Adhesin CD147 colorectal cancer fusobacterium nucleatum gut microbiota RadD Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Gut Microbes, Vol 16, Iss 1 (2024)
Druh dokumentu:	article
ISSN:	19490976 1949-0984 1949-0976
DOI:	10.1080/19490976.2024.2426617
Popis:	Fusobacterium nucleatum can promote colorectal cancer (CRC) development through a variety of virulence proteins. Zhang et al. recently identified an adhesin RadD, for Fusobacterium nucleatum adhesion to CRC. Targeting the interaction between RadD and CD147 will provide a new strategy for CRC treatment. This Commentary and View not only summarizes the research highlights but also discusses the possibility of targeted clearance of Fusobacterium nucleatum in clinical applications.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/0720ad72880e4aa09b7703677f6f4ff8 Zobrazit plný text záznamu View record in DOAJ