| Autor: |
Andre Pascal Kengne, Leon Tshilolo, Grace Ndeezi, Nicola Mulder, Moses Joloba, Victoria Nembaware, Nchangwi Syntia Munung, Vivian Paintsil, Emmanuel Peprah, Fred Stephen Sarfo, Deogratias Munube, Collen Masimirembwa, Ambroise Wonkam, Daniel Ansong, Kwaku Ohene-Frempong, Ezekiel Mupere, Sarah Kiguli, Julie Makani, Josephine Mgaya, Siana Nkya, Fred Semitala, Raphael Zozimus Sangeda, Emmanuel Balandya, Anazoeze Madu, Catherine Chunda-Liyoka, Yeya Dit Sadio Sarro, Daudi Jjingo, Obiageli Eunice Nnodu, Lulu Chirande, Boubacari Ali Touré, Aldiouma Guindo, Patience Kuona, Kevin Esoh, Mario Jonas, Maxwell Nwegbu, Upendo Masamu, Jack Morrice, Patrick Ohiani Moru, Valentina Ngo Bitoungui, Hans Ackerman, Alex Osei Akoto, Emmanuela Ambrose, Evans Amuzu, Samuel Asala, Biobele Brown, Mmbando Bruno, Daima Bukini, Pamela Gorejena, Abdul Aziz Hassan, Justin Hokororo, Jade Hotchkiss, Abdoul Malik Idris, Hezekiah Isa, Agnes Jonathan, Gwendoline Q. Kandawasvika, Daniel Kandonga, Ibrahima Keita, Sekou Kene, Frank Makundi, Janeth Manongi, Hamakwa Mantina, Jason Maro, Irene Kida Minja, Khuthala Mnika, Takudzwa Mtisi, Wilson Mupfururirwa, Ritah Mutagonda, Ruth Namazzi, Solomon Ofori-Aquah, Emmanuel Okocha, Fumni Olopade, Jesca Ondego, Chandré Oosterwyk-Liu, Nash Oyekanmi, Stella Paul, Cynthia Phiri, Paschal Ruggajo, Parker Ruhl, Ian Machingura Ruredzo, Pauline Sambo, Sawabati Shabani, Florence Urio, Robert Opoka |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
BMJ Open, Vol 14, Iss 11 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2044-6055 |
| DOI: |
10.1136/bmjopen-2024-089056 |
| Popis: |
Background Sickle cell disease (SCD) is a prevalent inherited blood disorder. Globally, approximately 515 000 babies are born with SCD annually, with 75% of these births occurring in Africa. Integrating newborn screening (NBS) for SCD into primary healthcare structures, such as immunisation programmes, holds significant promise, with dried blood spots (DBS)-point-of-care technologies (POCT) like HaemoTypeSC offering cost-effective screening solutions. However, scaling up DBS-POCT for NBS of SCD in Africa remains challenging.Objective This study aims to explore individual, organisational and external factors that may influence the reliability, feasibility, acceptability, adoption and sustainability of using DBS-POCT with HaemoTypeSC for NBS of SCD at primary healthcare centres in African countries.Method This qualitative study will be conducted in seven African countries that are part of the SickleInAfrica consortium sites. The study design is informed by the Consolidated Framework for Implementation Research (CFIR) and the Implementation Outcome Model. Participants will be mothers whose babies have been diagnosed with SCD, healthcare professionals and policy-makers. In-depth interviews and focus group discussions will be used for data collection. Data analysis will be through thematic analysis.Ethics and dissemination Research ethics approvals have been obtained from the seven countries. Written informed consent will be obtained from all participants. The study results will be disseminated in peer-reviewed scientific journals, scientific conferences, reports to national ministries of public health and webinars. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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