trans-Acting Factors and cis Elements Involved in the Human Inactive X Chromosome Organization and Compaction

Autor: Zhuo Sun, Jinbo Fan, Yufeng Zhao
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Genetics Research, Vol 2021 (2021)
Druh dokumentu: article
ISSN: 0016-6723
1469-5073
DOI: 10.1155/2021/6683460
Popis: During X chromosome inactivation, many chromatin changes occur on the future inactive X chromosome, including acquisition of a variety of repressive covalent histone modifications, heterochromatin protein associations, and DNA methylation of promoters. Here, we summarize trans-acting factors and cis elements that have been shown to be involved in the human inactive X chromosome organization and compaction.
Databáze: Directory of Open Access Journals
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