| Autor: |
Zahra Roumi, Zahra Salimi, Zahra Mahmoudi, Khadijeh Abbasi Mobarakeh, Maryam Ladaninezhad, Mobina Zeinalabedini, Mohammad Keshavarz Mohammadian, Ali Shamsi‐Goushki, Zahra Saeedirad, Bojlul Bahar, Sara Khoshdooz, Naser Kalantari, Ghasem Azizi Tabesh, Saeid Doaei, Maryam Gholamalizadeh |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Endocrinology, Diabetes & Metabolism, Vol 7, Iss 3, Pp n/a-n/a (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2398-9238 |
| DOI: |
10.1002/edm2.483 |
| Popis: |
ABSTRACT Background The FTO gene polymorphisms may influence the effects of lifestyle interventions on obesity. The present study aimed to assess the influence of the rs9930506 FTO gene polymorphism on the success of a comprehensive weight loss intervention in male adolescents with overweight and obesity. Methods This study was carried out on 96 adolescent boys with overweight and obesity who were randomly assigned to the intervention (n = 53) and control (n = 43) groups. The blood samples of the participants were collected, and the FTO gene was genotyped for the rs9930506 polymorphism. A comprehensive lifestyle intervention including changes in diet and physical activity was performed for 8 weeks in the intervention group. Results Following the lifestyle intervention, BMI and fat mass decreased significantly in the intervention group compared with the control group (both p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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