Endogenous Peptide Apelin and Pathological Cardiac Remodeling in Hypertensive Patients with Diabetes Mellitus Type 2

Autor: S.M. Koval, K.O. Yushko, T.H. Starchenko
Jazyk: English<br />Ukrainian
Rok vydání: 2015
Předmět:
Zdroj: Mìžnarodnij Endokrinologìčnij Žurnal, Vol 11, Iss 5.69, Pp 37-40 (2015)
Druh dokumentu: article
ISSN: 2224-0721
2307-1427
DOI: 10.22141/2224-0721.5.69.2015.75077
Popis: The study involved 63 patients with essential hypertension and diabetes mellitus type 2. The control group consisted of 16 apparently healthy individuals. Complex of examination included conventional clinical-laboratory and instrumental methods, ultrasound of the heart with Doppler sonography, determining apelin blood concentration by ELISA. Patients with essential hypertension and diabetes mellitus type 2 compared with the control group had a probable reduction in apelin level associated with the development of pathological cardiac remodeling, increasing the size of the left atrium and diastolic dysfunction of the heart.
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