Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano—Proof of Malignant Potential

Autor: Callie Blackford Winders, Cynthia M. Bell, Stephanie Goldschmidt
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Frontiers in Veterinary Science, Vol 7 (2020)
Druh dokumentu: article
ISSN: 2297-1769
DOI: 10.3389/fvets.2020.576376
Popis: A 1-year-old male Spinone Italiano dog was treated for an amyloid-producing odontogenic tumor on the right maxilla with a cytoreductive surgery followed by a definitive radiation protocol. Six years later, the dog presented for a new mass on the rostral mandible as well as a lung nodule without recurrence of the original maxillary tumor. Both the mandibular mass and the lung nodule were histologically confirmed to be amyloid-producing odontogenic tumor based on the appearance of sheets and cords of the odontogenic epithelium disrupted by amorphous extracellular amyloid. This case illustrates the metastatic potential for amyloid-producing odontogenic tumor in dogs and asynchronous occurrence of multiple APOTs in the oral cavity.
Databáze: Directory of Open Access Journals