Preliminary study on the short-term changes of pulmonary perfusion after a single balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension
| Autor: | Peng Hou, Hai-Ming Chen, Si-Yan Lin, Wen-Liang Guo, Peng-Hao Chen, Jie-Long Lin, Xiao-Feng Wu, Chun-Li Liu, Xin-Lu Wang, Cheng Hong |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Therapeutic Advances in Respiratory Disease, Vol 17 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1753-4666 17534666 |
| DOI: | 10.1177/17534666231212307 |
| Popis: | Background: Little is known about immediate responses of blood perfusion to the balloon pulmonary angioplasty (BPA) procedure. Objectives: To investigate the changes in pulmonary perfusion of balloon-dilated vessels and untreated vessels with before, immediately after a single BPA and at follow-up. Design: Retrospective single-center cohort study. Methods: Patients who had chronic thromboembolic pulmonary hypertension (CTEPH) and completed the pulmonary perfusion single photon emission computed tomography (SPECT) imaging before, immediately after BPA and at follow-up were included. We evaluated the perfusion defects of both-lung, BPA target (balloon dilated) and non-target (untreated) vessel segments according to Begic 3-point scale in each lung segment. Results: Forty patients (40 BPA procedures) were included and were given next BPA after 89 (62–125) days. The hemodynamic parameters including mPAP, PVR, and RAP were significantly improved after a single BPA. Visual scoring results of pulmonary perfusion imaging in 40 BPAs showed the perfusion defect scores of target vessels reduced from 5.6 ± 2.6 to 4.2 ± 2.2 ( p |
| Databáze: | Directory of Open Access Journals |
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