Transition from predictable to variable motor cortex and striatal ensemble patterning during behavioral exploration

Autor: Sravani Kondapavulur, Stefan M. Lemke, David Darevsky, Ling Guo, Preeya Khanna, Karunesh Ganguly
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-30069-1
Popis: It is not fully understood how behavioral flexibility is established in the context of automatic performance of a complex motor skill. Here the authors show that corticostriatal activity can flexibly transition between two modes during a reach to-grasp task in rats: reliable neural pattern generation for precise, automatic movements versus variable neural patterning for behavioral exploration.
Databáze: Directory of Open Access Journals