| Autor: |
Shah Dharati, Shah Atit, Patel Lata, Pethani Jayshri, Limbachia Urvashi, Shah Hiral |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Journal of Krishna Institute of Medical Sciences University, Vol 10, Iss 01, Pp 15-26 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2231-4261 |
| Popis: |
Background: Urinary Tract Infections (UTIs) are amongst the most common bacterial infections encountered. As there is an emergence of resistance in the uropathogens to multiple drugs, a local study regarding the sensitivity pattern of common uropathogens is necessary. Aim and Objectives: This study was aimed at analyzing the antimicrobial susceptibility pattern of prevalent uropathogens, isolated from patients at a tertiary care hospital in Ahmedabad. Material and Methods: The study was performed in the Department of Microbiology, Sardar Vallabhbhai Patel Hospital, N.H.L Municipal Medical College, Ahmedabad. Urine samples sent to the microbiology laboratory for culture and sensitivity over a period of one year were included in this study. Antimicrobial susceptibility testing was done on cultured isolates by VITEK 2-compact system (Biomerieux, France) following the manufacturer's instructions method as recommended in CLSI, 2020. Results: Out of a total of 6208 urine samples received, 1494 isolates obtained from 1484 culture-positive samples. The most commonly isolated organism was Escherichia coli (38.48%), followed by Klebsiella spp (14.85%) and Pseudomonas aeruginosa (10.30%). E. coli was most susceptible to fosfomycin (99.46%), colistin (98.43%), and tigecycline (97.39%). Klebsiella sppwere most susceptible to colistin (84.78%). Nearly, 75% strains of Klebsiella spp were showing resistance to Carbapenems due to Carbapenemase production. Conclusion: Overenthusiastic use of the antibiotic has resulted in the emergence of drug-resistant bacterial strains in patients. The study of antimicrobial susceptibility patterns of uropathogens in a particular area can guide the clinicians in the rational choice of empirical treatment to prevent the misuse of antibiotics. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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