Liver stiffness and arterial stiffness/abnormal central hemodynamics in the early stage of heart failure

Autor: Yoichi Iwasaki, Hirofumi Tomiyama, Kazuki Shiina, Chisa Matsumoto, Kazutaka Kimura, Masatsune Fujii, Yoshifumi Takata, Akira Yamashina, Taishiro Chikamori
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: International Journal of Cardiology: Heart & Vasculature, Vol 20, Iss , Pp 32-37 (2018)
Druh dokumentu: article
ISSN: 2352-9067
DOI: 10.1016/j.ijcha.2018.07.001
Popis: Background: It remains to be clarified whether liver stiffness is a direct risk factor for heart failure (HF) or whether its association with HF is mediated by vascular damage. We conducted cross-sectional and prospective longitudinal studies to examine whether fibrosis 4 score (FIB-4 score) is directly associated with the serum NT-pro-BNP levels or the association is mediated by arterial stiffness and/or abnormal central hemodynamics. Methods and results: In 3040 health Japanese subjects with serum NT-pro-BNP levels
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