A New View of a:C-H-coated Ti-6Al-4V Alloy to be Used as Orthopedic Implants: Influence of Surface Free-energy of Interaction on the Biological Responses

Autor: João Pedro Lopes do Nascimento, Leonardo dos Reis Freitas, Camila Nunes Lemos, Rogério Valentim Gelamo, Jeferson Aparecido Moreto
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Orbital: The Electronic Journal of Chemistry, Vol 13, Iss 3, Pp 264-268 (2021)
Druh dokumentu: article
ISSN: 1984-6428
DOI: 10.17807/orbital.v13i3.1622
Popis: In a previous published work, the Ti-6Al-4V alloy were functionalized by using plasma enhanced chemical vapour deposition (PECVD) process in order to obtain hydrogenated amorphous carbon (a:C-H) on the biomaterial's surface. At the time, we noticed the functionalized surface contributed to the advance of using Ti-6Al-4V in biomedical implants applications as well as in the adding of intrinsic properties as demonstrated by electrochemical and biological assays. Here, we present new view of a-C:H-coated Ti-6Al-4V alloy, considering the influence of surface free-energy of interaction and understanding how the surface influences the biological response using pre-osteoblastic cells (MC3T3-61). Our results demonstrate, the Ti-6Al-4V containing a:C-H film has less negative value of surface free-energy when compared to the bare material (-22.156 mJ m-2 vs. -60.046 mJ m-2), suggesting a tendency toward to a less hydrophobic surface which is extremely important to reduce the inflammatory process, common in orthopedic implants. DOI: http://dx.doi.org/10.17807/orbital.v13i3.1622
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