Autor: |
Hui Ming, Kunpeng Zhang, Shengbo Ge, Yang Shi, Chunan Du, Xuqiang Guo, Libo Zhang |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
|
Zdroj: |
Nanomaterials, Vol 13, Iss 2, p 224 (2023) |
Druh dokumentu: |
article |
ISSN: |
2079-4991 |
DOI: |
10.3390/nano13020224 |
Popis: |
As a potential therapeutic agent, the clinical application of S-nitrosoglutathione (GSNO) is limited because of its instability. Therefore, different formulations have been developed to protect GSNO from degradation, delivery and the release of GSNO at a physiological concentration in the active position. Due to the high water-solubility and small molecular-size of GSNO, the biggest challenges in the encapsulation step are low encapsulation efficiency and burst release. This review summarizes the different nano/micro-formulation strategies of a GSNO related delivery system to provide references for subsequent researchers interested in GSNO encapsulation. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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