| Autor: |
Ido Weiser-Bitoun, Hitoshi Mori, Taisuke Nabeshima, Naomichi Tanaka, Daisuke Kudo, Wataru Sasaki, Masataka Narita, Kazuhisa Matsumoto, Yoshifumi Ikeda, Takahide Arai, Shintaro Nakano, Naokata Sumitomo, Taka-aki Senbonmatsu, Kazuo Matsumoto, Ritsushi Kato, Christopher H. Morrell, Kenta Tsutsui, Yael Yaniv |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-023-45101-7 |
| Popis: |
Abstract Average beat interval (BI) and beat interval variability (BIV) are primarily determined by mutual entrainment between the autonomic-nervous system (ANS) and intrinsic mechanisms that govern sinoatrial node (SAN) cell function. While basal heart rate is not affected by age in humans, age-dependent reductions in intrinsic heart rate have been documented even in so-called healthy individuals. The relative contributions of the ANS and intrinsic mechanisms to age-dependent deterioration of SAN function in humans are not clear. We recorded ECG on patients (n = 16 |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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