Biomechanical parameter determination of scaffold-free cartilage constructs (SFCCs) with the hyperelastic material models Yeoh, Ogden and Demiray

Autor: Reuter T., Ponomarev I.
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Current Directions in Biomedical Engineering, Vol 1, Iss 1, Pp 442-445 (2015)
Druh dokumentu: article
ISSN: 2364-5504
DOI: 10.1515/cdbme-2015-0106
Popis: The biomechanical properties are crucial indicators for the functional characterization of cartilaginous tissue. In this contribution native articular cartilage and three-dimensional scaffold-free cartilage constructs (SFCCs) are characterized by hyperelastic material models (Yeoh, Ogden and Demiray). SFCCs were developed for the therapy of damaged articular cartilage. The normalized error (NE) of fit and experiment is in the range of 0.04 and 0.13. The material model Yeoh with two parameters yields the best fit. The stress-like parameterc20 is 0.489 MPa for native cartilage, 0.120 MPa and 0.041 MPa for SFCCs produced from mesenchymal stem cells and chondrocytes, respectively. The significance of the fits and the derived parameters are presented and evaluated.
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