| Autor: |
Rosa Helena de Figueiredo Chaves, Celice Cordeiro de Souza, Ismari Perini Furlaneto, Renan Kleber Costa Teixeira, Carolina Pinheiro de Oliveira, Emanuelle de Matos Rodrigues, Daniel Arthur Santos dos Santos, Renata Cunha Silva, Nelson Elias Abrahão da Penha, Ana Rita de Lima |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Acta Cirúrgica Brasileira, Vol 33, Iss 12, Pp 1087-1094 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
0102-8650 |
| DOI: |
10.1590/s0102-865020180120000006 |
| Popis: |
Abstract Purpose: To evaluate the influence tramadol on functional recovery of acute spinal cord injury in rats. Methods: Ten rats were divided into two groups (n = 5). All animals were submitted by a laminectomy and spinal cord injury at eighth thoracic vertebra. In control group, the rats didn’t receive any analgesic. In tramadol group, the rats received tramadol 4mg/Kg at 12/12h until 5 days by subcutaneous. Animals were following by fourteen days. Was evaluated the Basso, Beattie, Bresnahan scale (locomotor evaluation) and Rat Grimace Scale (pain evaluation) at four periods. Results: There no difference between the groups in locomotor evaluation in all periods evaluated (p>0.05) and in both groups there was a partial recover of function. The tramadol group show a lower pain levels at the first, third and seventh postoperatively days when comparing to the control group. Conclusion: The tramadol as an analgesic agent don’t influence on functional recovery of acute spinal cord injury in rats |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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