Longitudinal impact of bladder cancer diagnosis on common psychiatric disorders

Autor: Ian J. Cooke, Dattatraya Patil, Katherine Bobrek, Vikram Narayan, Viraj Master, Mark Rapaport, Christopher P. Filson, Shreyas S. Joshi
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Cancer Medicine, Vol 10, Iss 23, Pp 8412-8420 (2021)
Druh dokumentu: article
ISSN: 2045-7634
DOI: 10.1002/cam4.4346
Popis: Abstract Background The presence of psychiatric disorders in patients with cancer is associated with increased morbidity and poorer outcomes. We sought to determine the impact of a new bladder cancer diagnosis on the incidence of depression and anxiety. Methods We used a database of billing claims (MarketScan®) to identify patients newly diagnosed with bladder cancer between 2009 and 2018. Patients with preexisting psychiatric disorders or use of anxiolytics/antidepressants were excluded. We matched cases to patients without a bladder cancer or psychiatric diagnosis. Our primary outcome was a new diagnosis of depression, anxiety, or use of anxiolytics/antidepressants. Other exposures of interest included gender and treatment received. We used multivariable regression to estimate odds ratios for these exposures. Results We identified 65,846 cases with a new diagnosis of bladder cancer (31,367 privately insured; 34,479 Medicare‐eligible). Compared to controls, bladder cancer patients were more likely to develop new‐onset depression/anxiety at 6 months (privately insured: 6.9% vs. 3.4%, p
Databáze: Directory of Open Access Journals
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