Tuberculosis treatment delay and nosocomial exposure remain important risks for patients undergoing regular hemodialysis

Autor: Michael Lu, Yuh-Mou Sue, Han-Lin Hsu, Jun-Fu Zhang, Yi-Jun Liu, Yu-Chun Yen, Tzu-Yun Yu, Ming-Chih Yu, Chih-Hsin Lee
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Microbiology, Immunology and Infection, Vol 55, Iss 5, Pp 926-934 (2022)
Druh dokumentu: article
ISSN: 1684-1182
DOI: 10.1016/j.jmii.2021.08.011
Popis: Background and objective: Studies have reported an increased tuberculosis (TB) incidence among patients with end-stage renal disease (ESRD). This nationwide nested Case–control study investigated the risk of active TB due to nosocomial exposure and its correlation with the delay in TB treatment in hemodialysis patients. Methods: Adult (aged ≥20 years) patients with incident ESRD over 2000–2010 were identified from Taiwan National Health Insurance Research Database; 2331 patients with incident active TB (Case) were matched with 11,655 patients without TB (control) by age, sex, year of ESRD onset, Charlson comorbidity index, chronic obstructive pulmonary disease, and diabetes mellitus, at a 1:5 case-to-control ratio. Results: Compared with the control group, the Case group had greater nosocomial exposure to index patients with pulmonary TB (2.36 vs. 0.11 month of exposure, p
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