Successful immunosuppressive drug‐free immune tolerance induction in hemophilia B with inhibitor and anaphylaxis to factor IX: A case report

Autor: Ángeles Palomo Bravo, Rosario Prieto Bonilla, Daniel Bardan Rebollar, Francisco José López‐Jaime, Ihosvany Fernández‐Bello
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Clinical Case Reports, Vol 12, Iss 8, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2050-0904
DOI: 10.1002/ccr3.9312
Popis: Key Clinical Message Recommendations advise factor IX desensitization before immune tolerance induction in severe hemophilia B, supported by immunosuppression. A child with inhibitor and anaphylaxis to factor IX showed successful immunosuppression‐free immune tolerance induction using very low and slowly increasing doses of a factor IX extended‐half‐life product. Immune tolerance to factor IX based on this protocol merits further study.
Databáze: Directory of Open Access Journals
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