The profiles of miR-4510 expression level in breast cancer

Autor:	Sevan Omer Majed, Suhad Asad Mustafa
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Medicine Science
Zdroj:	Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Druh dokumentu:	article
ISSN:	2045-2322
DOI:	10.1038/s41598-022-25292-1
Popis:	Abstract MicroRNA that is abnormally produced in breast cells can disrupt biological processes, which can lead to cancer. This study aims to screen differentially expressed genes (DEGs) and ncRNAs (DEncRNAs) in the formalin-fixed paraffin-embedded (FFPE) tissues of breast cancer (BC) as compared with the normal adjacent tissues (NAT), and identify miR-4510 as a novel biomarker of BC. This study looked at differentially expressed genes (DEGs) using MACE-Seq and differentially expressed ncRNAs (DEncRNAs) using the small RNA-Seq. Real-time qPCR was used to determine the level of expression of miR-4510. In this study, MACE-Seq results showed that 26,795 genes, with a p-value
Databáze:	Directory of Open Access Journals
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