Human immunodeficiency virus infection is associated with greater risk of pneumonia and readmission after cardiac surgeryCentral MessagePerspective

Autor: Ali Vaeli Zadeh, MD, Alexander Justicz, MD, Juan Plate, MD, Michael Cortelli, MD, I-wen Wang, MD, PhD, John Nicholas Melvan, MD, PhD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: JTCVS Open, Vol 18, Iss , Pp 145-155 (2024)
Druh dokumentu: article
ISSN: 2666-2736
DOI: 10.1016/j.xjon.2024.01.002
Popis: Objective: Human immunodeficiency virus infection (HIV+) is associated with a 2-fold increased risk of cardiovascular disease. Increasingly, patients who are HIV + are being evaluated to undergo cardiac surgery. Current risk-adjusted scoring systems, including the Society of Thoracic Surgeons Predicted Risk of Mortality score, fail to stratify HIV + risk. Unfortunately, there exists a paucity of cardiac surgery outcomes data in modern patients who are HIV+. Methods: We conducted a retrospective review of PearlDiver, an all-payer claims administrative database. In total, 14,714,743 patients were captured between 2010 and 2020. Of these, 59,695 (0.4%) of patients had a history of HIV+, and 1759 (2.95%) of these patients underwent cardiac surgery. Patients who were HIV+ were younger, more often male, and had greater comorbidity, history of hypertension, chronic obstructive pulmonary disease, chronic liver disease, chronic kidney disease, chronic lung disease, and heart failure. Results: Postoperatively, patients who were HIV + had significantly greater rates of pneumonia (relative risk, 1.70; P = .0003) and 30-day all-cause readmission (relative risk, 1.28, P
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