| Autor: |
Ömür Kayıkçı, Özgür Mehtap, İsmail Sarı, Fatih Demirkan, Cengiz Beyan, Güven Çetin, Filiz Vural, Mehmet Yılmaz, Erman Öztürk, Seval Akpınar, Bülent Eser, Mehmet Gündüz, Yahya Büyükaşık, Bahriye Payzin, Rahşan Yıldırım, Mehmet Hilmi Doğu, Atilla Özkan, Engin Kelkitli, Emre Tekgündüz |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Turkish Journal of Hematology, Vol 39, Iss 3, Pp 170-177 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1308-5263 |
| DOI: |
10.4274/tjh.galenos.2022.2022.0052 |
| Popis: |
Objective: Peripheral T-cell lymphomas (PTCLs) are an uncommon and quite heterogeneous group of disorders, representing only 10%-15% of all non-Hodgkin lymphomas. Although both molecular and clinical studies have increased in recent years, we still have little knowledge regarding real-life practice with PTCLs. In this study, we aimed to investigate the clinical characteristics and treatment outcomes of a large population-based cohort of patients presenting with systemic non-cutaneous PTCL. Materials and Methods: We conducted a multicenter retrospective analysis of 190 patients consecutively diagnosed and treated with non-cutaneous PTCLs between 2008 and 2016. Results: Considering all first-line treatment combinations, the overall response rate was 65.9% with 49.4% complete remission (n=81) and 16.5% partial response (n=27). The 5-year overall survival and eventfree survival rates were significantly different between the transplant and non-transplant groups (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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