Methylation analysis by targeted bisulfite sequencing in large for gestational age (LGA) newborns: the LARGAN cohort

Autor:	Tamara Carrizosa-Molina, Natalia Casillas-Díaz, Iris Pérez-Nadador, Claudia Vales-Villamarín, Miguel Ángel López-Martínez, Rosa Riveiro-Álvarez, Larry Wilhelm, Rita Cervera-Juanes, Carmen Garcés, Alejandro Lomniczi, Leandro Soriano-Guillén
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Epigenome Markers Neonatal Cardiovascular Kidney Development Medicine Genetics QH426-470
Zdroj:	Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
Druh dokumentu:	article
ISSN:	1868-7083
DOI:	10.1186/s13148-023-01612-8
Popis:	Abstract Background In 1990, David Barker proposed that prenatal nutrition is directly linked to adult cardiovascular disease. Since then, the relationship between adult cardiovascular risk, metabolic syndrome and birth weight has been widely documented. Here, we used the TruSeq Methyl Capture EPIC platform to compare the methylation patterns in cord blood from large for gestational age (LGA) vs adequate for gestational age (AGA) newborns from the LARGAN cohort. Results We found 1672 differentially methylated CpGs (DMCs) with a nominal p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/064832d6e85c4a79bd8740221a102d45 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.