| Autor: |
Gehlot Prashasnika, Soyal Dhanraj, Goyal Pradeep K. |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Nuclear Technology and Radiation Protection, Vol 25, Iss 3, Pp 186-191 (2010) |
| Druh dokumentu: |
article |
| ISSN: |
1451-3994 |
| DOI: |
10.2298/NTRP1003186G |
| Popis: |
The radioprotective effect of the Aloe vera leaf extract was studied in Swiss albino mice against radiation-induced changes in the liver. The mice were treated with 1000 mg/kg of body weight orally, once a day for 15 consecutive days, before exposure to a single dose of gamma radiation (6 Gy), half an hour after the last administration. The irradiation of mice caused a significant elevation in lipid peroxidation followed by a decrease in glutathione, acid phosphatase and alkaline phosphatase. The treatment of mice before irradiation elevated the glutathione, acid phosphatase and alkaline phosphatase, and was accompanied by a decline in lipid peroxidation. Recovery and regeneration from radiation damage were faster in pretreated animals than the animals in the irradiation-only group. The data clearly indicate that the Aloe vera leaf extract significantly reduced the deleterious effects of radiation on the liver and it could be a useful agent in reducing the side effects of therapeutic radiation. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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