Effect of an educational intervention on the number potential drug-drug interactions

Autor: Aigul Z. Mussina, Gaziza A. Smagulova, Galina V. Veklenko, Bibigul B. Tleumagambetova, Nazgul A. Seitmaganbetova, Aigul A. Zhaubatyrova, Lazzat M. Zhamaliyeva
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Saudi Pharmaceutical Journal, Vol 27, Iss 5, Pp 717-723 (2019)
Druh dokumentu: article
ISSN: 1319-0164
DOI: 10.1016/j.jsps.2019.04.007
Popis: Background: The objective of this study was to evaluate effect of an Educational intervention on the number Potential Drug-Drug Interactions in the Emergency Hospital. Methods: The prevalence and structure of Major Drug-Drug Interactions at Emergency care Hospitals of Aktobe, Uralsk, Atyrau cities (Kazakhstan) were studied (pharmacoepidemiological, cross-sectional study). Educational interventions were developed and implemented to improve pharmacotherapy in the Cardiology Department of the Aktobe Emergency Hospital, followed by an assessment of their effect. Results: The effect of educational interventions was revealed, which led to a significant decrease in the indicators of drug interactions of the Major Drug-Drug Interactions by 18.2% (OR: 0.45; 95% CI, 0.25-to-0.82) in the cardiological patients of the Emergency Care Hospital of Aktobe city compared to the Regional Cardiology Center of Uralsk. Conclusion: The implementation of educational pharmacotherapy programs decreased the number of clinically significant drug interactions in the Cardiology Department of Emergency Hospitals. Keywords: Pharmacotherapy, Drug-drug interaction, Education, Cardiology
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