Isolation and Structural Elucidation of Chondrosterins F–H from the Marine Fungus Chondrostereum sp.

Autor:	Wen-Jian Lan, Xiao-Feng Zhu, Ying-Lu Xie, Wen-Dan Chen, Hou-Jin Li, Ting Chen
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Chondrostereum sp. sesquiterpenoids chondrosterins marine fungus cytotoxic activities Biology (General) QH301-705.5
Zdroj:	Marine Drugs, Vol 11, Iss 2, Pp 551-558 (2013)
Druh dokumentu:	article
ISSN:	1660-3397 20539304
DOI:	10.3390/md11020551
Popis:	The marine fungus Chondrostereum sp. was collected from a soft coral of the species Sarcophyton tortuosum from the South China Sea. Three new compounds, chondrosterins F–H (1, 4 and 5), together with three known compounds, incarnal (2), arthrosporone (3), and (2E)-decene-4,6,8-triyn-1-ol (6), were isolated. Their structures were elucidated primarily based on NMR and MS data. Incarnal (2) exhibited potent cytotoxic activity against various cancer cell lines.
Databáze:	Directory of Open Access Journals
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