| Autor: |
Violeta Ramos-Sesma, Miriam Navarro, Jara Llenas-García, Concepción Gil-Anguita, Diego Torrús-Tendero, Philip Wikman-Jorgensen, Concepción Amador-Prous, María-Paz Ventero-Martín, Ana-María Garijo-Sainz, María García-López, Ana-Isabel Pujades-Tárraga, Cristina Bernal-Alcaraz, Antonio Santonja, Pedro Guevara-Hernández, María Flores-Chávez, José-María Saugar, José-Manuel Ramos-Rincón, Corazones Sin Chagas Platform |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Pathogens, Vol 9, Iss 6, p 511 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2076-0817 |
| DOI: |
10.3390/pathogens9060511 |
| Popis: |
Strongyloides stercoralis infection is frequently underdiagnosed since many infections remain asymptomatic. Aim: To estimate the prevalence and characteristics of asymptomatic S. stercoralis infection in Latin American migrants attending a community-based screening program for Chagas disease in Spain. Methodology: Three community-based Chagas disease screening campaigns were performed in Alicante (Spain) in 2016, 2017, and 2018. Serological testing for S. stercoralis infection was performed using a non-automatized IVD-ELISA detecting IgG (DRG Instruments GmbH, Marburg, Germany). Results: Of the 616 migrants from Central and South America who were screened, 601 were included in the study: 100 children and adolescents (S. stercoralis infection was more common in men than in women (odds ratio adjusted [ORa] 2.28, 95% CI 1.289 to 4.03) and in those from Bolivia (ORa 2.03, 95% CI 1.15 to 3.59). Prevalence increased with age (ORa 1.02, 95% CI 0.99 to 1.05). In contrast, a university education had a protective effect (ORa 0.29, 95% CI 0.31 to 0.88). Forty-one (41/66; 62.1%) of the total cases of S. stercoralis infection were treated at the health care center. Positive stool samples were observed in 19.5% of the followed-up positive cases. Conclusion: Incorporating serological screening for S. stercoralis into community-based screening for Chagas disease is a useful intervention to detect asymptomatic S. stercoralis infection in Central and South American migrants and an opportunity to tackle neglected tropical diseases in a transversal way. The remaining challenge is to achieve patients’ adherence to the medical follow-up. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
