A combined behavioral and pharmacological approach in nonparaneoplastic-related anti-N-methyl-D-aspartate receptor encephalitis: A case report with positive outcome in a male patient

Autor: Matthew Rong Jie Tay, Karen Sui Geok Chua
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: The Journal of the International Society of Physical and Rehabilitation Medicine, Vol 3, Iss 1, Pp 22-27 (2020)
Druh dokumentu: article
ISSN: 2589-9457
DOI: 10.4103/jisprm.jisprm_3_20
Popis: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a rare but potentially life-threatening and disabling autoimmune encephalitis mainly affecting young women. We report the case of a male in his early thirties who developed behavioral and neurocognitive manifestations of anti-NMDAR encephalitis. This case highlights the unique behavioral challenges in a male patient during the course of rehabilitation, including impulsivity, inappropriate sexual behavior, and hyperphagia, which has not been well-described in the literature. This presented complex problems for the rehabilitation team and amelioration of these clinical issues required a multidisciplinary approach. The behavioral and pharmacological strategies employed, which had a pronounced positive contribution in this patient, are described. A brief review of the epidemiology, course, and common complications of anti-NMDAR encephalitis is also presented.
Databáze: Directory of Open Access Journals