ARFI shear-wave elastography with simulation of acute urinary tract obstruction in an ex vivo porcine kidney model
| Autor: | Jens Muttray, Arianeb Mehrabi, Mohammadreza Hafezi, Arash Saffari, Thi Thanh Tam Bui-Ta, Jochen Meyburg, Elke Wühl, Jens Peter Schenk |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Diagnostic and Interventional Radiology, Vol 24, Iss 5, Pp 308-315 (2018) |
| Druh dokumentu: | article |
| ISSN: | 1305-3825 1305-3612 |
| DOI: | 10.5152/dir.2018.17353 |
| Popis: | PURPOSE:We aimed to evaluate if acoustic radiation force impulse (ARFI) shear-wave elastography (SWE) can detect change of parenchymal stiffness in an ex vivo porcine kidney model of acute urinary tract obstruction.METHODS:A total of 20 heparinized pig kidneys were investigated at 10 intrapelvic hydrostatic pressure steps (0–90 mmHg). SWE (ARFI; Virtual TouchTM IQ, Siemens) measurements were taken at three different measuring regions and in two measuring sequences using a linear ultrasonography probe (9L4, Siemens). Median values of 10 shear-wave speed (SWS) measurements were calculated for each pressure step. Logarithmic transformed median SWS values were analyzed in a linear mixed model.RESULTS:SWS increased significantly with increasing intrapelvic pressure. Median SWS for all kidneys in both measuring sequences and all measuring regions was 1.47 m/s (interquartile range [IQR], 0.38 m/s) at 0 mmHg, 1.94 m/s (IQR, 0.42 m/s) at 30 mmHg, 2.07 m/s (IQR, 0.43 m/s) at 60 mmHg, 2.24 m/s (IQR, 0.49 m/s) at 90 mmHg. The correlation between pelvic pressure increase and median SWS values for the central parenchyma was significantly higher compared with the peripheral parenchyma.CONCLUSION:Acutely increased renal pelvic pressure correlates with increasing SWS values in ARFI elastography in an ex vivo porcine kidney model. |
| Databáze: | Directory of Open Access Journals |
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