Outcomes of surgical versus transcatheter aortic valve replacement in nonagenarians- a systematic review and meta-analysis

Autor: Azka Latif, Muhammad Junaid Ahsan, Noman Lateef, Vikas Kapoor, Mohsin Mansoor Mirza, Faiz Anwer, Michael Del Core, Arun Kanmantha Reddy
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 1, Pp 128-134 (2021)
Druh dokumentu: article
ISSN: 2000-9666
20009666
DOI: 10.1080/20009666.2020.1843235
Popis: Introduction: Since the approval of transcatheter aortic valve replacement (TAVR), nonagenarian group patients are being increasingly considered for TAVR. Therefore, we compared the clinical outcomes of surgical aortic valve replacement (SAVR) vs TAVR in nonagenarians with severe aortic stenosis. Methods: A literature search was performed using MEDLINE, Embase, Web of Science, Cochrane, and Clinicaltrials.gov for studies reporting the comparative outcomes of TAVR versus SAVR in nonagenarians. The primary endpoint was short-term mortality. Secondary endpoints were post-operative incidences of stroke or transient ischemic attack (TIA), vascular complications, acute kidney injury (AKI), transfusion requirement, and length of hospital stay. Results: Four retrospective studies qualified for inclusion with a total of 8,389 patients (TAVR = 3,112, SAVR = 5,277). Short-term mortality was similar between the two groups [RR = 0.91 (95% CI: 0.76–1.10), p = 0.318]. The average length of hospital stay was shorter by 3 days in the TAVR group (p = 0.037). TAVR was associated with a significantly lower risk of AKI [RR = 0.72 (95% CI: 0.62–0.83), p
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