An Overview of Supramolecular Platforms Boosting Drug Delivery

Autor: Rosa Bellavita, Simone Braccia, Annarita Falanga, Stefania Galdiero
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Bioinorganic Chemistry and Applications, Vol 2023 (2023)
Druh dokumentu: article
ISSN: 1687-479X
DOI: 10.1155/2023/8608428
Popis: Numerous supramolecular platforms inspired by natural self-assembly are exploited as drug delivery systems. The spontaneous arrangement of single building blocks into inorganic and organic structures is determined and controlled by noncovalent forces such as electrostatic interactions, π-π interactions, hydrogen bonds, and van der Waals interactions. This review describes the main structures and characteristics of several building blocks used to obtain stable, self-assembling nanostructures tailored for numerous biological applications. Owing to their versatility, biocompatibility, and controllability, these nanostructures find application in diverse fields ranging from drug/gene delivery, theranostics, tissue engineering, and nanoelectronics. Herein, we described the different approaches used to design and functionalize these nanomaterials to obtain selective drug delivery in a specific disease. In particular, the review highlights the efficiency of these supramolecular structures in applications related to infectious diseases and cancer.
Databáze: Directory of Open Access Journals
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