Analgesic effect of hydroalcoholic extract of Zingiber and piper nigrum in mice by tail-flick test

Autor: M.R H EIDARI, F Sharififar, M Salmani-Befrouei
Jazyk: angličtina
Rok vydání: 1997
Předmět:
Zdroj: Journal of Kerman University of Medical Sciences, Vol 4, Iss 3, Pp 107-113 (1997)
Druh dokumentu: article
ISSN: 2008-2843
Popis: in traditional medicine,some plants have been used as analysics.the aim of this investigation was to evaluate the analgesic effect of two plants,piper nigrum and Zingiber officinale that are used traditionally to relieve headache,rheumatic arthritis,and toothache.for this purpose the methanolic extract of zingiber and piper nigrum,in different doses,were injected intraperitonealy to mice and the analgesic effect was determined by tail-flick apparatus.the results show that the suxhleted extract of piper nigrum with dose of 50 and 75 mg/kg of body weight did not induce significant analgesia in comparison to the control group but of 100mg/kg induced significant analgesia.this analgesia effect was maximum at 90 min after injection of the extract (p
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