Challenges and outcome of Wilms′ tumour management in a resource-constrained setting

Autor: Wilde J.C.H, Lameris W, van Hasselt E, Molyneux E, Heij H, Borgstein E
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: African Journal of Paediatric Surgery, Vol 7, Iss 3, Pp 159-162 (2010)
Druh dokumentu: article
ISSN: 0189-6725
0974-5998
Popis: Background: To review the results of Wilms′ tumour patients in a tertiary referral hospital in a developing country and to find ways of improving long-term survival. Patients and Methods: Between January 1998 and May 2004, 40 patients with Wilms′ tumour (WT) were admitted to Queen Elizabeth Central Hospital. Their files were reviewed and general physical condition on admission, pre-operative investigations, management and outcome were noted. Results: The mean age of presentation was 4.2 years with an equal distribution between the sexes. The mean BMI was 15 kg/m2 and more than 80% of the patients were either mildly (PCV Conclusion: The patients presented in an advanced stage of the disease. Survival rates are disappointing and recurrence rates are high. Some improvement in outcome may be expected with the implementation of more aggressive treatment protocols but early diagnosis, completion of treatment regimens are needed. Pro-active follow-up is essential to measure outcome.
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