| Autor: |
Dong-ri Piao, Xi Liu, Dong-dong Di, Pei Xiao, Zhong-zhi Zhao, Li-qing Xu, Guo-zhong Tian, Hong-yan Zhao, Wei-xing Fan, Bu-yun Cui, Hai Jiang |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
BMC Microbiology, Vol 18, Iss 1, Pp 1-6 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2180 |
| DOI: |
10.1186/s12866-018-1149-0 |
| Popis: |
Abstract Background Brucellosis incidence in China is divided into three stages: high incidence (1950s–1960s), decline (1970s–1980s), and re-emergence (1990s–2010s). At the re-emergence stage, Brucellosis incidence grew exponentially and spread to all 32 provinces. We describe the magnitude and the etiological distribution changes in mainland China by genotyping data and emphasize its recent reemergence. We also provide the genetic diversity and molecular epidemiological characteristics of Brucella. Results From a total of 206 Brucella isolates, 19 MLST genotypes (STs) were identified and 13 new STs(ST71–83)were found. MLST grouped the population into three clusters. B. melitensis, B. abortus and B. suis were grouped into cluster 1, 2 and 3 respectively. The predominant genotype in the first cluster by MLST, remained unchanged during the three stages. However, the proportion of genotypes in the three stages had changed. More isolates were clustered in ST8 at the re-emergence stage. STs71–74, which were not found in the two former stages, appeared at the re-emergence stage. Conclusions The changing molecular epidemiology of brucellosis improve our understanding of apparent geographic expansion from the historically affected north of China to southern provinces in recent reemergence. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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